Codeine is transformed to morphine in the body. Many people adjust codeine to morphine much more rapidly than others. These people today are named "extremely-swift metabolizers of codeine". Get in touch with your physician instantly if you encounter Serious sleepiness, confusion, or shallow breathing.
It is unidentified if this medication passes into breast milk. Nevertheless, it could possibly have undesirable outcomes with a nursing infant. Speak to your health care provider right before breastfeeding.
Promethazine hydrochloride wasn't mutagenic within the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary (CHO) cell chromosomal aberration assay.
Urine drug screening, capsule counts, caregiver or member of the family encounters, and prescription monitoring method facts might be helpful monitoring applications for patients on stable doses and that has a lower chance for adverse outcomes; checking just about every 3 to 6 months may very well be adequate. Weekly checking is a reasonable tactic for individuals at higher hazard for abuse.[24]
This drug could make you dizzy or drowsy or blur your vision. Liquor or marijuana (cannabis) could make you more dizzy or drowsy. Will not generate, use machinery, or do everything that demands alertness or distinct vision until finally you are able to do it safely and securely.
Promethazine is a phenothiazine spinoff, which differs structurally in the antipsychotic phenothiazines from the existence of a branched aspect chain and no ring substitution.
The Drug Enforcement Administration classifies codeine and hydrocodone within their pure varieties as Agenda II drugs. This implies they've a large probable for misuse and can lead to serious Bodily or psychological dependence.
Unneeded remedies needs to be disposed of in Exclusive means to make certain Animals, young children, and Other individuals can not eat them. Even so, you shouldn't flush this medication down the toilet. In its place, The easiest way to dispose of your medication is thru a medication consider-back again method.
Codeine and promethazine, two on the active components in Promethazine with Codeine Oral Answer, could create marked drowsiness and impair the psychological and/or Actual physical abilities expected with the overall performance of doubtless hazardous jobs including driving a car or truck or operating machinery. Advise sufferers to stop partaking in harmful responsibilities necessitating psychological alertness and motor coordination just after ingestion of Promethazine with Codeine Oral Solution.
Promethazine with Codeine Oral Remedy may perhaps result in critical hypotension like orthostatic hypotension and syncope in ambulatory people. There's elevated danger in sufferers whose ability to keep up blood pressure level has now been compromised by a decreased blood volume or concurrent administration of selected CNS depressant prescription drugs (e.
When codeine is employed for many years or in significant doses, it may become routine-forming, creating psychological or Actual physical dependence. Physical dependence may perhaps bring about Promethazine codeine syrup withdrawal Negative effects any time you out of the blue stop getting the drugs.
approach to avoid unneeded or extended publicity to sunlight and to have on protective garments, sun shades, and sunscreen. Promethazine may make the skin delicate to sunlight.
Choose this medication by mouth with or with out food stuff as directed by your medical professional, ordinarily each and every 4 to 6 several hours as required. This medication is usually taken with food stuff if stomach upset takes place. Consume an abundance of fluids whenever you use this medication Unless of course or else directed by your medical doctor.
Test along with your wellness treatment Skilled if any of the following Unintended effects carry on or are bothersome or if you have any questions about them: